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Showing 10 out of a total of 47 results for community: Fakülteler.
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Novel morpholine liganded Pd-based N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure, antidiabetic and anticholinergic properties
Aktaş, Aydın
;
Celepci, Duygu Barut
;
Kaya, Ruya
;
Taslimi, Parham
;
Gök, Yetkin
;
Aygün, Muhittin
;
Gülçin, İlhami
(
POLYHEDRON
,
2019-02-01
)
Synthesis and investigation of anticancer, antibacterial activities and carbonic anhydrase, acetylcholinesterase inhibition profiles of novel (3aR,4S,7R,7aS)-2-[4-[1-acetyl-5-(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-diones
Kocyigit, Umit M.
;
Budak, Yakup
;
Gürdere, Meliha Burcu
;
Dürü, Neşe
;
Taslimi, Parham
;
Gülçin, İlhami
;
Ceylan, Mustafa
(
MONATSHEFTE FUR CHEMIE
,
2019-04
)
Synthesis, characterization, crystal structure, electrochemical studies and biological evaluation of metal complexes with thiosemicarbazone of glyoxylic acid
Huseynova, Mansura
;
Taslimi, Parham
;
Medjidov, Ajdar
;
Farzaliyev, Vagif
;
Aliyeva, Mahizar
;
Gondolova, Gulnar
;
Şahin, Onur
;
Yalçın, Bahattin
;
Sujayev, Afsun
;
Orman, Efe Baturhan
;
Özkaya, Ali Rıza
;
Gulçin, İlhami
(
Elsevier
,
2018-11-15
)
In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4‐dihydro‐3H‐1,2, 4‐triazole‐3‐thiones—Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles
Timur, İrfan
;
Kocyigit, Ümit M.
;
Dastan, Taner
;
Sandal, Süleyman
;
Ceribası, Ali Osman
;
Taslimi, Parham
;
Gulcin, İlhami
;
Koparir, Metin
;
Karatepe, Mustafa
;
Çiftç, Mehmet
(
Wiley
,
2019-01
)
Meta-Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, -glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties
Turker, Ferhat
;
Celepci, Duygu Barut
;
Celepci, Duygu Barut
;
Aktaş, Aydın
;
Taslimi, Parham
;
Gök, Yetkin
;
Aygün, Muhittin
;
Gülçin, İlhami
(
Wiley
,
2018-07
)
Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes
Demir, Yeliz
;
Taslimi, Parham
;
Ozaslan, Muhammet Serhat
;
Oztaskin, Necla
;
Çetinkaya, Yasin
;
Gulçin, İlhami
;
Beydemir, Şükrü
;
Goksu, Suleyman
(
Wiley
,
2018-12
)
Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer’s disease
Türkan, Fikret
;
Taslimi, Parham
;
Zerrin Saltan, Fatma
(
Wiley
,
2019-03-25
)
Novel sulfamate derivatives of menthol: Synthesis, characterization, and cholinesterases and carbonic anhydrase enzymes inhibition properties
Daryadel, Shahla
;
Atmaca, Ufuk
;
Taslimi, Parham
;
Gülçin, İlhami
;
Çelik, Murat
(
Wiley
,
2018-11
)
Multiple studies have been recorded on the synthesis and design of multi‐aim anti‐Alzheimer molecules. Using dual butyrylcholinesterase/acetylcholinesterase inhibitor molecules has attracted more interest in the therapy for Alzheimer’s disease. In this study, a tannic acid compound showed excellent inhibitory effects against acetylcholine esterase (AChE), α‐glycosidase, α‐amylase, and butyrylcholinesterase (BChE). IC50 values of tannic acid obtained 11.9 nM against α‐glycosidase and 3.3 nM against α‐amylase, respectively. In contrast, Ki values were found of 50.96 ± 2.18 μM against AChE and 53.17 ± 4.47 μM against BChE. α‐Glycosidase inhibitor compounds can be utilized as a novel group of antidiabetic drugs. By competitively decreasing glycosidase activity, these inhibitor molecules help to hamper the fast breakdown of sugar molecules and thereby control the blood sugar level.
Kaya, Ruya
;
Taslimi, Parham
;
Naldan, Muhammet Emin
;
Gulçin, İlhami
(
Bentham Science
,
2019
)
Synthesis, characterization and crystal structure of 2-(4-hydroxyphenyl)ethyl and 2-(4-nitrophenyl)ethyl Substituted Benzimidazole Bromide Salts: Their inhibitory properties against carbonic anhydrase and acetylcholinesterase
Behçet, Ayten
;
Çağlılar, Tuba
;
Celepci, DuyguBarut
;
Aktaş, Aydın
;
Taslimi, Parham
;
Gök, Yetkin
;
Aygün, Muhittin
;
Kaya, Ruya
;
Gülçin, İlhami
(
Elsevier
,
2018-10-15
)
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Author
Taslimi, Parham (43)
Ilhami, Gulcin (14)
Gulçin, İlhami (10)
Gulcin, Ilhami (8)
Gülçin, İlhami (8)
Supuran, Claudiu T. (6)
Turkan, Fikret (5)
Afsun, Sujayev (4)
Goksu, Suleyman (4)
Gök, Yetkin (4)
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Subject
Enzyme inhibition (47)
Carbonic anhydrase (35)
Acetylcholinesterase (26)
Butyrylcholinesterase (11)
Enzyme purification (5)
Antidiabetic (4)
Antioxidant activity (4)
Anticholinergics (3)
Bromophenols (3)
Crystal structure (3)
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Date Issued
2019 (15)
2018 (18)
2017 (6)
2016 (7)
2015 (1)