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Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes 

Kucukoglu, Kaan; Gul, Halise Inci; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (Bioorganic Chemistry, 2019-02-04)
Recently, inhibition of carbonic anhydrase (hCA) and acetylcholinesterase (AChE) have appeared as a promising approach for pharmacological intervention in a variety of disorders such as glaucoma, epilepsy, obesity, cancer, ...
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The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products 

Bayrak, Cetin; Taslimi, Parham; Karaman, Halide Sedef; Gulcin, Ilhami; Menzek, Abdullah (Bioorganic Chemistry, 2019-04)
Starting from vanillin, known four benzyl bromides with Br were synthesized. The first synthesis of natural product 3,4-dibromo-5-((methylsulfonyl)methyl)benzene-1,2-diol (2) and 3,4,6-tribromo-5-((methylsulfonyl) ...

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Gulcin, Ilhami (2)
Taslimi, Parham (2)Bayrak, Cetin (1)Gul, Halise Inci (1)Karaman, Halide Sedef (1)Kucukoglu, Kaan (1)Menzek, Abdullah (1)Supuran, Claudiu T. (1)SubjectAcetylcholinesterase (2)
Carbonic anhydrase (2)
Enzyme inhibition (2)Bromination (1)Bromophenol (1)Hydrazone (1)Mannich base (1)Molecular docking (1)... View MoreDate Issued
2019 (2)
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