Search

Now showing items 1-3 of 3

The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase enzymes

Cetin, Bayrak; Taslimi, Parham; Ilhami, Gulcin; Abdullah, Menzek (Elsevier, 2017-06)

The first synthesis of (E)-4-(3-bromo-4,5-dihydroxyphenyl) but-3-en-2-one (1), (E)-4-(2-bromo-4,5-dihy droxyphenyl) but-3-en-2-one (2), and (E)-4-(2,3-dibromo-4,5-dihydroxyphenyl) but-3-en-2-one (3) was realized as natural ...

Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions

Ilhami, Gulcin; Taslimi, Parham; Öztaşkın, Necla; Göksu, Süleyman; Maraş, Ahmet (Elsevier, 2017-10)

In this study, a series of novel bromophenols were synthesized from benzoic acids and methoxylated bromophenols. The synthesized compounds were evaluated by using different bioanalytical antioxidant assays including ...

The effects of some bromophenols on human carbonic anhydrase isoenzymes

Taslimi, Parham; Gulcin, Ilhami; Oztaskin, Necla; Cetinkaya, Yasin; Goksu, Suleyman; Alwasel, Saleh H.; Supuran, Claudiu T. (Informa, 2016)

Carbonic anhydrases (CAs, EC 4.2.1.1), which are involved in a variety of physiological and pathological processes, are ubiquitous metalloenzymes mainly catalyzing the reversible hydration of carbon dioxide (CO2) to ...