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Antidiabetic potential: in vitro inhibition effects of some natural phenolic compounds on -glycosidase and -amylase enzymes 

Parham, Taslimi; Ilhami, Gulcin (Wiley, 2017-10)
-Glycosidase is a catalytic enzyme and it destroys the complex carbohydrates into simple absorbable sugar units. The natural phenolic compounds were tested for their antidiabetic properties as -glycosidase and -amylase ...
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2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, alpha-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties 

Fatos, Erdemir; Duygu Barut, Celepci; Aydin, Aktas; Parham, Taslimi; Yetkin, Gok; Hasan, Karabiyik; Ilhami, Gulcin (Elsevier, 2018-03-05)
This study contains novel a serie synthesis of N-heterocyclic carbene (NHC) precursors that 2-hydroxyethyl substituted. The NHC precursors have been prepared from 1-(2-hydroxyethyl)benzimidazole and alkyl halides. The novel ...
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The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues 

Fikret, Turkan; Zubeyir, Huyut; Parham, Taslimi; Ilhami, Gulcin (Wiley, 2018-03)
In this paper, the in vivo effects of some antibiotics including cefazolin, cefuroxime, and cefoperazon, on the activity of the carbonic anhydrase enzyme (CA) in heart, brain, eye, liver, and kidney tissues of rats were ...
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Synthesis and bioactivity of several new hetaryl sulfonamides 

Parham, Taslimi; Afsun, Sujayev; Sevgi, Mamedova; Pinar, Kalin; Ilhami, Gulcin; Nastaran, Sadeghian; Sukru, Beydemir; O. Irfan, Kufrevioglu; Saleh H., Alwasel; Vagif, Farzaliyev; Sabir, Mamedov (Informa, 2017)
1-(4-Methylsulfonyl)-2-thione-4-aryl-5-Z-6-methyl and oxyalkyl-imidazoles were synthesized from different tetrahydropyrimidinethiones and aryl sulfonyl chloride. These compunds were tested for metal chelating effects and ...
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Synthesis and investigation of the conversion reactions of pyrimidine-thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities 

Parham, Taslimi; Afsun, Sujayev; Fikret, Turkan; Emin, Garibov; Zubeyir, Huyut; Vagif, Farzaliyev; Sevgi, Mamedova; Ilhami, Gulcin (Wiley, 2018-02)
The conversion reactions of pyrimidine-thiones with nucleophilic reagent were studied during this scientific research. For this purpose, new compounds were synthesized by the interaction between 1,2-epoxy propane, 1,2-epoxy ...
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Synthesis and investigation of antibacterial activities and carbonic anhydrase and acetyl cholinesterase inhibition profiles of novel 4,5-dihydropyrazol and pyrazolyl-thiazole derivatives containing methanoisoindol-1,3-dion unit 

Yakup, Budak; Umit M., Kocyigit; Meliha Burcu, Gurdere; Kezban, Ozcan; Parham, Taslimi; Ilhami, Gulcin; Mustafa, Ceylan (Taylor & Francis, 2017)
Novel 4,5-dihydropyrazole derivatives (3a-i), 3-(4-((3aR,4S,7R,7aS)-1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothio amide, were obtained by the addition ...
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Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base 

Parham, Taslimi; Sabiya, Osmanova; Ilhami, Gulcin; Sabira, Sardarova; Vagif, Farzaliyev; Afsun, Sujayev; Ruya, Kaya; Fatma, Koc; Sukru, Beydemir; Saleh H., Alwasel; Omer Irfan, Kufrevioglu (Wiley, 2017-09)
Compounds containing nitrogen and sulfur atoms can be widely used in various fields, including industry, medicine, biotechnology, and chemical technology. Among them, amides of acids and heterocyclic compounds have an ...
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Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines 

Halise Inci, Gul; Parham, Taslimi; Ilhami, Gulcin; Claudiu T., Supuran (Informa, 2017)
4-(3-(4-Substituted-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamides (9-16) were successfully synthesized and their chemical structures were confirmed by H-1 NMR, C-13 NMR, and HRMS spectra. Carbonic ...

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AuthorIlhami, Gulcin (8)
Parham, Taslimi (8)
Afsun, Sujayev (3)Vagif, Farzaliyev (3)Fikret, Turkan (2)Saleh H., Alwasel (2)Sevgi, Mamedova (2)Sukru, Beydemir (2)Zubeyir, Huyut (2)Aydin, Aktas (1)... View MoreSubjectCarbonic anhydrase (7)Acetylcholinesterase (4)Enzyme inhibition (4)Butyrylcholinesterase (2)Acetophenone (1)alpha-Glycosidase (1)Amylase (1)Antibacterial activity (1)Antioxidant activity (1)Aryl sulfonyl chlorides (1)... View MoreDate Issued2017 (5)2018 (3)Has File(s)No (8)

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