Predictors of relapse in patients with opioid addiction during buprenorphine-naloxone maintenance treatment
Özet
Background: Opioid abuse is an important public health issue.
Buprenorphine-Naloxone Combination (BNC) is one of the most
efficacious approaches for opioid withdrawal. Thus it is important
to determine factors related with treatment outcomes in BNC
maintenance treatment. Thus, we aimed to evaluate the predictors of
three months compliance rate with BNC treatment among a sample
of patients with opioid addiction.
Methods: In this retrospective study, we evaluated the records of
patients who sought and had received any treatment with BNC for
opioid addiction in an addiction treatment center during three months
period. Relevant data such as socio-demographic variables, drug
use history, and opioid use patterns were gathered from the records.
Results: At least three months after BNC maintenance treatment,
relapse rate was 66.6%. Patients who were not married and those
with an education of less than 8 years were more likely to relapse
to opioid use. We also found a relationship between average
daily heroin doses and relapse as reflected by illicit opioid use during
treatment.
Conclusions: Future research is needed to reveal whether
determining these factors and establishing adequate interventions
may lead to improved treatment outcomes.
