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Yayın tarihi için Biyoteknoloji Bölümü Makale Koleksiyonu listeleme

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    • Küçük Resim

      Five complexes containing N,N-bis(2hydroxyethyl)-ethylenediamine with tetracyanidopalladate(II): synthesis, crystal structures, thermal, magnetic, and catalytic properties 

      Korkmaz, Nesrin; Karadağ, Ahmet (Taylor & Francis, 2013-08-14)
      Five cyanide complexes, [Ni(N-bishydeten)Pd(CN)4]( 1), [Cu(N-bishydeten)Pd(μ-CN)2(CN)2]n (2), [Cu(N-bishydeten)2][Pd(CN)4]( 3), [Zn(N-bishydeten)Pd(CN)4]( 4), and [Cd(N-bishydeten)2][Pd (CN)4]( 5)(N-bishydeten = ...
    • Küçük Resim

      Removal of some textile dyes from aqueous solution by using a catalase-peroxidase from aeribacillus pallidus (P26) 

      Nadaroglu, H.; Adiguzel, A.; Bozoglu, C.; Gulluce, M.; Taslimi, Parham (Oriental Scientific Pub. Co., 2013-12)
      The textile dyeing wastewater is discharged to the environment in various occasions and causes severe environmental problems. Therefore, more effective treatment methods should be developed to eliminate dyes from the ...
    • Küçük Resim

      Synthesis and characterization of two novel dicyanidoargentate(I) complexes containing N-(2-hydroxyethyl)ethylenediamine exhibiting significant biological activity 

      Korkmaz, Nesrin; Karadağ, Ahmet (Royal Society of Chemistry, 2014-07-05)
      Two novel cyanido-bridged bimetallic polymeric complexes, [Ni(hydeten)2Ag(CN)2] [Ag(CN) 2] H2O(C1) and [Cd2(hydeten)2Ag4(CN)8] H2O( C2) (hydeten: N-(2-hydroxyethyl)ethylenediamine) were synthesized and characterized by ...
    • Küçük Resim

      Anticancer activities and mechanism of action of 2 novel metal complexes, C16H34N8O5Ag2Cd and C11H16N7O2Ag3Ni 

      Korkmaz, Nesrin; Karadağ, Ahmet (TÜBİTAK, 2014-11-24)
      The discovery of anticancer activity in cisplatin triggered the development of novel drugs containing metals such as platinum or ruthenium. Extremely diverse structural chemistry and the interaction of metal complexes with ...
    • Küçük Resim

      Two new coordination polymers containing dicyanidoargentate(I) and dicyanidoaurate(I): synthesis and characterization, and a detailed in vitro investigation of their anticancer activities on some cancer cell lines 

      Korkmaz, Nesrin; Karadağ, Ahmet (TÜBİTAK, 2015-02-16)
      Two novel cyanido-bridged bimetallic polymeric complexes, [Ni(edbea)Ag3 (CN)5]n (C1) and [Ni(bishydeten) Au2 (CN)4 ]n (C2), where edbea = [2,2′-(ethylenedioxy)bis(ethylamine)] and bishydeten = [(N ,N′-bis(2-hydroxyethyl) ...
    • Küçük Resim

      Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives 

      Oztaskin, Necla; Cetinkaya, Yasin; Taslimi, Parham; Goksu, Suleyman; Gulcin, Ilhami (Elsevier, 2015-06)
      In this study, series of novel bromophenol derivatives were synthesized and investigated for their antioxidant and AChE inhibition properties. Novel brominated diarylmethanones were obtained from the acylation reactions ...
    • Küçük Resim

      Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides 

      Gul, Halise Inci; Tugrak, Mehtap; Sakagami, Hiroshi; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (Informa, 2016)
      A series of new 4-(3-(4-substitutedphenyl)-3a, 4-dihydro-3H-indeno[1,2-c] pyrazol-2-yl) benzenesulfonamides (7-12) was synthesized starting from 2-(4-substitutedbenzylidene)-2,3-dihydro-1H-inden-1-one (1-6) and ...
    • Küçük Resim

      The effects of some bromophenols on human carbonic anhydrase isoenzymes 

      Taslimi, Parham; Gulcin, Ilhami; Oztaskin, Necla; Cetinkaya, Yasin; Goksu, Suleyman; Alwasel, Saleh H.; Supuran, Claudiu T. (Informa, 2016)
      Carbonic anhydrases (CAs, EC 4.2.1.1), which are involved in a variety of physiological and pathological processes, are ubiquitous metalloenzymes mainly catalyzing the reversible hydration of carbon dioxide (CO2) to ...
    • Küçük Resim

      Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase 

      Sujayev, Afsun; Garibov, Emin; Taslimi, Parham; Gulcin, Ilhami; Gojayeva, Sevinj; Farzaliyev, Vagif; Alwasel, Saleh H.; Supuran, Claudiu T. (Informa, 2016)
      2-(Methacryloyloxy)ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate, is a cyclic urea derivative synthesized from urea, 2-(methacryloyloxy) ethyl acetoacetate and substituted benzaldehyde, and tested ...
    • Küçük Resim

      Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects 

      Gul, Halise Inci; Kucukoglu, Kaan; Yamali, Cem; Bilginer, Sinan; Yuca, Hafize; Ozturk, Iknur; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (Informa, 2016)
      In this study, 4-(2-substituted hydrazinyl)benzenesulfonamides were synthesized by microwave irradiation and their chemical structures were confirmed by H-1 NMR, (CNMR)-C-13, and HRMS. Ketones used were: Acetophenone (S1), ...
    • Küçük Resim

      Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase 

      Ozgun, Dilan Ozmen; Yamali, Cem; Gul, Halise Inci; Taslimi, Parham; Gulcin, Ilhami; Yanik, Telat; Supuran, Claudiu T. (Informa, 2016)
      The effects of isatin Mannich bases incorporating (1-[piperidin-1-yl (P1)/morpholin-4-yl (P2)/N-methylpiperazin-1-yl (P3)]methyl)-1H-indole-2,3-dione) moieties against human (h) carbonic anhydrase (CA, EC 4.2.1.1) isoenzymes ...
    • Küçük Resim

      The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives 

      Taslimi, Parham; Gulcin, Ilhami; Ozgeris, Bunyamin; Goksu, Suleyman; Tumer, Ferhan; Alwasel, Saleh H.; Supuran, Claudiu T. (Informa, 2016-01)
      Carbonic anhydrases (CAs, EC 4.2.1.1) had six genetically distinct families described to date in various organisms. There are 16 known CA isoforms in humans. Human CA isoenzymes I and II (hCA I and hCA II) are ubiquitous ...
    • Küçük Resim

      Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities 

      Emin, Garibov; Taslimi, Parham; Afsun, Sujayev; Zeynebe, Bingol; Songul, Cetinkaya; Ilhami, Gulcin; Sukru, Beydemir; Vagif, Farzaliyev; Saleh H., Alwasel; Claudiu T., Supuran (Informa, 2016-12)
      A series of tetrahydropyrimidinethiones were synthesized from thiourea, -diketones and aromatic aldehydes, such as p-tolualdehyde, p-anisaldehyde, o-tolualdehyde, salicylaldehyde and benzaldehyde. These cyclic thioureas ...
    • Küçük Resim

      Antioxidant activity, acetylcholinesterase, and carbonic anhydrase inhibitory properties of novel ureas derived from phenethylamines 

      Kadir, Aksu; Bunyamin, Ozgeris; Taslimi, Parham; Ali, Naderi; Ilhami, Gulcin; Suleyman, Goksu (Wiley, 2016-12)
      A series of ureas derived from phenethylamines were synthesized and evaluated for human carbonic anhydrase (hCA) I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzyme inhibitory activities and ...
    • Küçük Resim

      The synthesis of some beta-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles 

      Turan, Burhanettin; Sendil, Kivilcim; Sengul, Emin; Gultekin, Mehmet Serdar; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (Informa, 2016-12)
      beta-Lactam antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a beta-lactam ring in their molecular structures. Synthesis of beta-lactam analogs, which are containing dichloride ...
    • Küçük Resim

      Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions 

      Ozbey, Fadime; Taslimi, Parham; Gulcin, Ilhami; Maras, Ahmet; Goksu, Sueleyman; Supuran, Claudiu T. (Informa, 2016-12)
      A series of diaryl ethers were synthesized and their human (h) carbonic anhydrase (CA) isoenzymes hCA I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) inhibitory actions were investigated. The new ...
    • Küçük Resim

      Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors 

      Ilhami, Gulcin; Malahat, Abbasova; Taslimi, Parham; Zubeyir, Huyut; Leyla, Safarova; Afsun, Sujayev; Vagif, Farzaliyev; Sukru, Beydemir; Saleh H., Alwasel; Claudiu T., Supuran (Informa, 2017)
      Compounds containing nitrogen and sulfur atoms can be widely used in various fields such as industry, medicine, biotechnology and chemical technology. Therefore, the reactions of aminomethylation and alkoxymethylation of ...
    • Küçük Resim

      Synthesis and bioactivity of several new hetaryl sulfonamides 

      Parham, Taslimi; Afsun, Sujayev; Sevgi, Mamedova; Pinar, Kalin; Ilhami, Gulcin; Nastaran, Sadeghian; Sukru, Beydemir; O. Irfan, Kufrevioglu; Saleh H., Alwasel; Vagif, Farzaliyev; Sabir, Mamedov (Informa, 2017)
      1-(4-Methylsulfonyl)-2-thione-4-aryl-5-Z-6-methyl and oxyalkyl-imidazoles were synthesized from different tetrahydropyrimidinethiones and aryl sulfonyl chloride. These compunds were tested for metal chelating effects and ...
    • Küçük Resim

      Synthesis and investigation of antibacterial activities and carbonic anhydrase and acetyl cholinesterase inhibition profiles of novel 4,5-dihydropyrazol and pyrazolyl-thiazole derivatives containing methanoisoindol-1,3-dion unit 

      Yakup, Budak; Umit M., Kocyigit; Meliha Burcu, Gurdere; Kezban, Ozcan; Parham, Taslimi; Ilhami, Gulcin; Mustafa, Ceylan (Taylor & Francis, 2017)
      Novel 4,5-dihydropyrazole derivatives (3a-i), 3-(4-((3aR,4S,7R,7aS)-1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothio amide, were obtained by the addition ...
    • Küçük Resim

      Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines 

      Halise Inci, Gul; Parham, Taslimi; Ilhami, Gulcin; Claudiu T., Supuran (Informa, 2017)
      4-(3-(4-Substituted-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamides (9-16) were successfully synthesized and their chemical structures were confirmed by H-1 NMR, C-13 NMR, and HRMS spectra. Carbonic ...

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