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Synthesis of mannich bases by two different methods and evaluation of their acetylcholine esterase and carbonic anhydrase inhibitory activities

Halise I., Gul; Alkan, Demirtas; Gokbay, Ucar; Taslimi, Parham; Ilhami, Gulcin (Letters in Drug Design & Discovery, 2017)

Background: Mannich bases are an important compounds in medicinal chemistry. They have wide range of biological activities including carbonic anhydrase (CA) inhibitory and acetylcholine esterase inhibitory (AChE) activities. ...