The Effects of Regular Treadmill Exercise on Some Blood Parameters in Diabetes Mellitus

Abstract

This study aims to determine the effects of regular treadmill exercise on some blood parameters in rats with an experimental diabetes model. In the study, 36 Wistar Albino rats were divided into four groups Control (C), Exercise (E), Diabetes (D), and Diabetes+Exercise (DE). A single dose of 60 mg/kg STZ solution was injected intraperitoneally (i.p) into the D and DE groups to create a diabetes model. After diabetes induction, E and DE groups were given running exercises at 20 m/min and 45 minutes daily for four weeks. According to the data obtained, while lipid profile (TC, LDL, TG) and liver enzyme (ALT, AST) levels increased significantly in group D compared to group C, HDL and TP levels were found to decrease. However, a decrease was observed in parameters other than HDL and TP in the DE group. It was also observed that the mineral and vitamin (Vit D, Ca, Mg, and Zn) levels decreased in the D group compared to the C group, while these values tended to increase in the DE group. As a result, the experiment shows that a four week regular exercise program in rats with diabetes has a therapeutic, preventive, and protective effect on lipoprotein levels, liver enzyme markers, and micronutrient levels.