CEPHALARIA SYRIACA (L.): INVESTIGATION OF ANTIMICROBIAL, ANTIBIOFILM, ANTIOXIDANT POTENTIAL AND SEED MORPHOLOGY

Abstract

Plants that have been used in the treatment of many diseases for centuries are now used for industrial and medical purposes. Cephalaria genera in the Dipsacaceae family have properties such as mitigating and relaxing. Cephalaria syriaca L., commonly found in Anatolia, is generally used in industry due to the fatty acids it contains. It is also used as the additive to wheat flour. This study aimed to investigate the antibacterial activity of DMSO extracts of oil derived from the seed of Cephalaria syriaca (L.) grown in Turkey against twenty bacterial strains. For this purpose, disk diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal/bacteriostatic concentration (MBC) methods were used. Antifungal activity of DMSO extracts against a fungus strain was examined by disc diffusion method. Antioxidant activities of seed oil extracts were investigated using DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay. In addition, seed morphology was examined using a stereomicroscope and scanning electron microscope (SEM). In conclusion, the extracts had the highest antibacterial activity against Staphylococcus epidermidis and Enterobacter aerogenes extracts, and the highest antibiofilm activity against Proteus vulgaris, with 39.94 +/- 9.25%.