Ara
Toplam kayıt 119, listelenen: 61-70
Novel benzylic substituted imidazolinium, tetrahydropyrimidinium and tetrahydrodiazepinium salts: potent carbonic anhydrase and acetylcholinesterase inhibitors
(2018-07-23)
The new imidazolinium, tetrahydropyrimidinium and tetrahydrodiazepinium salts were synthesized in good yield by the reaction of the corresponding N,N'-dialkylalkanediamine with triethyl orthoformate in the presence of ...
Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects
(Wiley, 2019-03)
Novel substituted thiophene derivatives (1, 2a-e, 3, and 4) were synthesized and their structures were characterized by infrared radiation, nuclear magnetic resonance, and mass analysis. These novel substituted thiophene ...
Tannik asidin tavşan karaciğerinde flavin monooksijenaz, sitokrom p450 ve antioksidan enzim aktiviteleri üzerine in vitro etkileri
(2010-06-25)
Giriş: Bu çalışmada bitki fenolik bileşiklerinden tannik asidin ilaçlar ve çeşitli kimyasal bileşiklerin metabolizmasında rol alan enzimler ile antioksidan enzim sistemleri üzerine in vitro etkileri incelenmiştir.
Gereç ...
Novel morpholine liganded Pd-based N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure, antidiabetic and anticholinergic properties
(POLYHEDRON, 2019-02-01)
This study involves the synthesis of novel N-heterocyclic carbene (NHC)PdX2(morpholine) complexes (1a-i). These Pd-based complexes are synthesized from pyridine enhanced precatalyst preparation stabilization and initiation ...
Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes
(Bioorganic Chemistry, 2019-02)
In this study, a series of novel bis-thiomethylcyclohexanone compounds (3a-3j) were synthesized by the addition of thio-Michael to the bis-chalcones under mild reaction conditions. The bis-thiomethylcyclohexanone derivatives ...
Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials
(Elsevier, 2018-12)
A series of classical and newly synthesized thymol bearing oxypropanolamine compounds were synthesized and characterized. Their in vitro antibacterial activity on A. baumannii, P. aeruginosa, E. coli and S. aureus strains ...
Synthesis, characterization, crystal structure of the coordination polymer Zn(II) with thiosemicarbazone of glyoxalic acid and their inhibitory properties against some metabolic enzymes
(Bioorganic Chemistry, 2019-03)
A new coordination polymer Zn(II) with thiosemicarbazone glyoxalic acid H(2)GAT was obtained in this study. According to the X-ray diffraction data, the coordination of the Zn(II) ion is carried out by one sulfur atom, in ...
In vivo effects of o-coumaric acid on rat liver flavin-containing monooxygenase (fmo) activity and expression
(2012-06-29)
Phenolic compounds are biologically active molecules and suggested to have some disease-preventive properties such as cardiovascular and certain types of cancer. Coumaric acid has been known as a phenolic compound and found ...
Yeni siyano köprülü heteronükleer koordinasyon kompleksleri ve bunların farmasötik madde olarak kullanımı
(Türk Patent Enstitüsü, 2013-08-22)
Buluş, yeni dinükleer siyano köprülü koordinasyon polimerleriyle ilgilidir. Daha özel bir ifadeyle buluş metal iyonlarının, yani bakır, çinko veya kadmiyumun 2,2'-(etilendioksi)bis(etilamin) ligandı ve disiyanoargentat ...
Schiff bases and their amines: Synthesis and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors
(Wiley, 2018-09)
Three series of symmetrical Schiff bases were synthesized from 1,2-diaminoethane, 1,3-diaminopropane and 1,4-diaminobutane and substituted benzaldehydes, and reduced by sodium borohydride to the corresponding benzylic ...