Yazar "Taslimi, Parham" için Fen Fakültesi listeleme
Toplam kayıt 77, listelenen: 41-60
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Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α‐amylase, butyrylcholinesterase, and α‐glycosidase enzymes
Bursal, Ercan; Aras, Abdulmelik; Kılıç, Ömer; Taslimi, Parham; Gören, Ahmet C.; Gülçin, İlhami (Journal Of Food Biochemistry, 2019-03)Many taxa of Salvia genus have been used in herbal beverages, food flavoring, cosmetics, and pharmaceutical industry. In this paper, chemical compounds of Salvia eriophora (S. eriophora) leaves were determined by LC-MS/MS ... -
Removal of some textile dyes from aqueous solution by using a catalase-peroxidase from aeribacillus pallidus (P26)
Nadaroglu, H.; Adiguzel, A.; Bozoglu, C.; Gulluce, M.; Taslimi, Parham (Oriental Scientific Pub. Co., 2013-12)The textile dyeing wastewater is discharged to the environment in various occasions and causes severe environmental problems. Therefore, more effective treatment methods should be developed to eliminate dyes from the ... -
Schiff bases and their amines: Synthesis and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors
Yiğit, Beyhan; Yiğit, Murat; Taslimi, Parham; Gök, Yetkin; Gülçin, İlhami (Wiley, 2018-09)Three series of symmetrical Schiff bases were synthesized from 1,2-diaminoethane, 1,3-diaminopropane and 1,4-diaminobutane and substituted benzaldehydes, and reduced by sodium borohydride to the corresponding benzylic ... -
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
Eruygur, N; Kocyigit, U.M.; Taslimi, Parham; Atas, M.; Tekin, M.; Gulcin, I. (Elsevier, 2019-01)The Achillea genus belongs to the Asteraceae family, which is mostly found in the northern hemisphere and is comprised of 115 species in the world. In Turkish flora, there are 52 species and 58 taxa, among them half of ... -
Some pyrazoles derivatives: Potent carbonic anhydrase, α‐glycosidase, and cholinesterase enzymes inhibitors
Turkan, Fikret; Cetin, Adnan; Taslimi, Parham; Gulçin, İlhami (Wiley, 2018-10)A series of substituteed pyrazol-4-yl-diazene derivatives were found to be effective inhibitors against -glycosidase, cytosolic carbonic anhydrase I and II isoforms (hCA I and II), butyrylcholinesterase (BChE), and ... -
Sulfonamide inhibitors: a patent review 2013-present
Ilhami, Gulcin; Taslimi, Parham (Expert Opinion on Therapeutic Patents, 2018)Introduction: Sulfonamide compounds are significant class of synthetic bacteriostatic antibiotics still which used today for the therapy of bacterial infections and those caused by other microorganisms. They are also known ... -
Synephrine and phenylephrine act as -amylase, -glycosidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase enzymes inhibitors
Taslimi, Parham; Akıncıoğlu, Hülya; İlhami, Gülçin (Wiley, 2017-11)In this paper, synephrine and phenylephrine compounds showed excellent inhibitory effects against human carbonic anhydrase (hCA) isoforms I and II, -amylase, -glycosidase, acetylcholinesterase (AChE), and butyrylcholinesterase ... -
Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides
Gul, Halise Inci; Tugrak, Mehtap; Sakagami, Hiroshi; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (Informa, 2016)A series of new 4-(3-(4-substitutedphenyl)-3a, 4-dihydro-3H-indeno[1,2-c] pyrazol-2-yl) benzenesulfonamides (7-12) was synthesized starting from 2-(4-substitutedbenzylidene)-2,3-dihydro-1H-inden-1-one (1-6) and ... -
Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors
Ilhami, Gulcin; Malahat, Abbasova; Taslimi, Parham; Zubeyir, Huyut; Leyla, Safarova; Afsun, Sujayev; Vagif, Farzaliyev; Sukru, Beydemir; Saleh H., Alwasel; Claudiu T., Supuran (Informa, 2017)Compounds containing nitrogen and sulfur atoms can be widely used in various fields such as industry, medicine, biotechnology and chemical technology. Therefore, the reactions of aminomethylation and alkoxymethylation of ... -
Synthesis and biological evaluation of phloroglucinol derivatives possessing -glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase inhibitory activity
Serdar, Burmaoglu; Ali O., Yilmaz; Taslimi, Parham; Oztekin, Algul; Deryanur, Kilic; Ilhami, Gulcin (Wiley, 2018-02)A series of novel phloroglucinol derivatives were designed, synthesized, characterized spectroscopically and tested for their inhibitory activity against selected metabolic enzymes, including -glycosidase, acetylcholinesterase ... -
Synthesis and carbonic anhydrase inhibition of tetrabromo chalcone derivatives
Ilhami, Gulcin; Koçyiğit, Ümit M.; Budak, Yakup; Fikret, Eligüzel; Taslimi, Parham; Kılıç, Deryanur; Ceylan, Mustafa (Wiley, 2017-12)In the present study, human carbonic anhydrase (hCA) enzyme was purified and characterized from fresh blood human red cells by Sepharose-4B-l-tyrosine-sulfanilamide affinity gel chromatography. Secondly, a series of new ... -
Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects
Cetin, Adnan; Türkan, Fikret; Taslimi, Parham; Gulçin, İlhami (Wiley, 2019-03)Novel substituted thiophene derivatives (1, 2a-e, 3, and 4) were synthesized and their structures were characterized by infrared radiation, nuclear magnetic resonance, and mass analysis. These novel substituted thiophene ... -
Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and alpha-glycosidase enzymes inhibitors: The novel N,N '-bis-cyanomethylamine and alkoxymethylamine derivatives
Taslimi, Parham; Cuneyt, Caglayan; Vagif, Farzaliyev; Oruj, Nabiyev; Afsun, Sujayev; Fikret, Turkan; Ruya, Kaya; Ilhami, Gulcin (Wiley, 2018-04)During this investigation, N,N'-bis-azidomethylamines, N,N'-bis-cyanomethylamine, new alkoxymethylamine and chiral derivatives, which are considered to be a new generation of multifunctional compounds, were synthesized, ... -
Synthesis and investigation of anticancer, antibacterial activities and carbonic anhydrase, acetylcholinesterase inhibition profiles of novel (3aR,4S,7R,7aS)-2-[4-[1-acetyl-5-(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-diones
Kocyigit, Umit M.; Budak, Yakup; Gürdere, Meliha Burcu; Dürü, Neşe; Taslimi, Parham; Gülçin, İlhami; Ceylan, Mustafa (MONATSHEFTE FUR CHEMIE, 2019-04)A series of novel 1,3,5-trisubstituted pyrazoline derivatives, (3aR,4S,7R,7aS)-2-[4-[1-acetyl-5-(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-diones, were ... -
Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities
Emin, Garibov; Taslimi, Parham; Afsun, Sujayev; Zeynebe, Bingol; Songul, Cetinkaya; Ilhami, Gulcin; Sukru, Beydemir; Vagif, Farzaliyev; Saleh H., Alwasel; Claudiu T., Supuran (Informa, 2016-12)A series of tetrahydropyrimidinethiones were synthesized from thiourea, -diketones and aromatic aldehydes, such as p-tolualdehyde, p-anisaldehyde, o-tolualdehyde, salicylaldehyde and benzaldehyde. These cyclic thioureas ... -
Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects
Gul, Halise Inci; Kucukoglu, Kaan; Yamali, Cem; Bilginer, Sinan; Yuca, Hafize; Ozturk, Iknur; Taslimi, Parham; Gulcin, Ilhami; Supuran, Claudiu T. (Informa, 2016)In this study, 4-(2-substituted hydrazinyl)benzenesulfonamides were synthesized by microwave irradiation and their chemical structures were confirmed by H-1 NMR, (CNMR)-C-13, and HRMS. Ketones used were: Acetophenone (S1), ... -
Synthesis of chalcone-imide derivatives and investigation of their anticancer and antimicrobial activities, carbonic anhydrase and acetylcholinesterase enzymes inhibition profiles
Umit Muhammet, Kocyigit; Yakup, Budak; Meliha Burcu, Gurdere; Fatih, Erturk; Belkiz, Yencilek; Taslimi, Parham; Ilhami, Gulcin; Mustafa, Ceylan (Taylor & Francis, 2018)The new 1-(4-(3-(aryl)acryloyl)phenyl)-1H-pyrrole-2,5-diones (5a-g) were prepared from 4-aminchalcones (3a-g) and screened for biological activities. All compounds (3a-g and 5a-g), except 3d and 3e displayed good cytotoxic ... -
Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions
Ozbey, Fadime; Taslimi, Parham; Gulcin, Ilhami; Maras, Ahmet; Goksu, Sueleyman; Supuran, Claudiu T. (Informa, 2016-12)A series of diaryl ethers were synthesized and their human (h) carbonic anhydrase (CA) isoenzymes hCA I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) inhibitory actions were investigated. The new ... -
Synthesis of mannich bases by two different methods and evaluation of their acetylcholine esterase and carbonic anhydrase inhibitory activities
Halise I., Gul; Alkan, Demirtas; Gokbay, Ucar; Taslimi, Parham; Ilhami, Gulcin (Letters in Drug Design & Discovery, 2017)Background: Mannich bases are an important compounds in medicinal chemistry. They have wide range of biological activities including carbonic anhydrase (CA) inhibitory and acetylcholine esterase inhibitory (AChE) activities. ... -
Synthesis of new cyclic thioureas and evaluation of their metal-chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles
Taslimi, Parham; Afsun, Sujayev; Emin, Garibov; Nazar, Nazarov; Zubeyir, Huyut; Saleh H., Alwasel; Ilhami, Gulcin (Wiley, 2017-07)In the presence of trifluoracetic acid (TFAA), an efficient method for the synthesis of tetra(hexa)hydropyrimidinethione-carboxylates has been used on the basis of three-component condensation of thiourea with its different ...