Browsing Fen Fakültesi by Author "Umit M., Kocyigit"
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Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes
Umit M., Kocyigit; Taslimi, Parham; Hayreddin, Gezegen; Ilhami, Gulcin; Mustafa, Ceylan (Wiley, 2017-09)Carbonic anhydrase (CA; EC 4.2.1.1) is used for remedial purposes for several years, as there is significant focus on expanding more new activators (CAAs) and high affinity inhibitors. Alzheimers disease and other similar ... -
The Inhibitory effects of some drugs on carbonic anhydrase enzyme purified from Kangal Akkaraman sheep in Sivas, Turkey
Umit M., Kocyigit; Sevgi Durna, Dastan; Taslimi, Parham; Taner, Dastan; Ilhami, Gulcin (Wiley, 2018-01)In this study, carbonic anhydrase (CA) enzyme was purified and characterized from blood samples of Kangal Akkaraman sheep and inhibitory properties on certain antibiotics were examined. CA purification was composed of ... -
Synthesis and investigation of antibacterial activities and carbonic anhydrase and acetyl cholinesterase inhibition profiles of novel 4,5-dihydropyrazol and pyrazolyl-thiazole derivatives containing methanoisoindol-1,3-dion unit
Yakup, Budak; Umit M., Kocyigit; Meliha Burcu, Gurdere; Kezban, Ozcan; Parham, Taslimi; Ilhami, Gulcin; Mustafa, Ceylan (Taylor & Francis, 2017)Novel 4,5-dihydropyrazole derivatives (3a-i), 3-(4-((3aR,4S,7R,7aS)-1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothio amide, were obtained by the addition ... -
Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles
Nilufer, Bulut; Umit M., Kocyigit; Ibrahim H., Gecibesler; Taner, Dastan; Huseyin, Karci; Taslimi, Parham; Sevgi Durna, Dastan; Ilhami, Gulcin; Ahmet, Cetin (Wiley, 2018-01)Some novel derivatives of thiosemicarbazide and 1,2,4-triazole-3-thiol were synthesized and evaluated for their biological activities. The title compounds were prepared starting from readily available pyridine-2,5-dicarboxylic ...