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Ebeveynlerin bilgi güvenliği farkındalıklarının incelenmesi
(Eğitim Teknolojisi Kuram ve Uygulama, 2017-06-01)
Bilgi ve iletişim teknolojilerinin (BİT) gelişmesiyle birlikte bu araçların günlük hayatımızdaki kullanımları da hızla artmaktadır. BİT’in hayatımıza sağlamış olduğu pek çok yararın yanında, birçok güvenlik problemine de ...
Prediction of internet addiction of university students based on various variables
(2014)
Üniversite öğrencilerinin internet bağımlılıklarının çeşitli değişkenler açısından incelenmesi İnternetin hızla geliştiği ve maliyetinin hızla düştüğü bu teknolojiyi kullananların sayısını hızla artıyor. İnternet, kullanıcılar ...
Synthesis and carbonic anhydrase inhibition of tetrabromo chalcone derivatives
(Wiley, 2017-12)
In the present study, human carbonic anhydrase (hCA) enzyme was purified and characterized from fresh blood human red cells by Sepharose-4B-l-tyrosine-sulfanilamide affinity gel chromatography. Secondly, a series of new ...
Deltohelicoidal surfaces
(2019-09-06)
The surface theory has been working by many mathematicians, and also geometers for hundreds of years. We meet nice papers and books for the theory in the literature. In this paper, we consider deltohelicoidal surface in ...
The first synthesis and antioxidant and anticholinergic activities of 1-(4,5-dihydroxybenzyl)pyrrolidin-2-one derivative bromophenols including natural products
(Turkish Journal of Chemistry, 2018)
We report herein the first synthesis of biologically active natural bromophenols, namely 1-(2,3,6-tribromo-4,5-dihydroxybenzyl)pyrrolidin-2-one (2), 2RS-1- (2 ,3-dibromo-4 ,5-dihydroxybenz yl)-5-oxopyrrolidine-2-carboxylic ...
Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes
(Wiley, 2017-09)
Carbonic anhydrase (CA; EC 4.2.1.1) is used for remedial purposes for several years, as there is significant focus on expanding more new activators (CAAs) and high affinity inhibitors. Alzheimers disease and other similar ...
Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles
(Wiley, 2018-01)
Some novel derivatives of thiosemicarbazide and 1,2,4-triazole-3-thiol were synthesized and evaluated for their biological activities. The title compounds were prepared starting from readily available pyridine-2,5-dicarboxylic ...
Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with N‐salicyloil‐N′‐maleoil‐hydrazine as anticholinergic and antidiabetic agents
(Wiley, 2018-09)
[Ni(C11H9N2O5)(2)(H2O)(2)]center dot 3(C3H7NO) (1) and [Co(C11H9N2O5)(2)(H2O)(2)]center dot 3(C3H7NO) (2) are synthesized and characterized by elemental analysis, FT-IR spectra, magnetic susceptibility, and thermal analysis. ...
Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and alpha-glycosidase enzymes inhibitors: The novel N,N '-bis-cyanomethylamine and alkoxymethylamine derivatives
(Wiley, 2018-04)
During this investigation, N,N'-bis-azidomethylamines, N,N'-bis-cyanomethylamine, new alkoxymethylamine and chiral derivatives, which are considered to be a new generation of multifunctional compounds, were synthesized, ...
The effects of some antibiotics from cephalosporin groups on the acetylcholinesterase and butyrylcholinesterase enzymes activities in different tissues of rats
(Taylor & Francis, 2019-01-01)
In our study, it was aimed to investigate the effects of cefazolin, cefuroxime, and cefoperazon injected to rats on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzyme activities in the heart, brain, eye, ...