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Toplam kayıt 57, listelenen: 31-40
Examining the relationship between pre-service teachers’ educational technology and material development competency and their techno-pedagogical competency
(2017)
Although digital technologies signify innovation and prestige, adopting such technology in teaching praxis requires deeperunderstanding and examination of technology integration with different variables. This study examines ...
The effect of structure in flipped classroom designs for deep and surface learning approaches
(Turkish Online Journal of Educational Technology, 2017-04-01)
A growing body of research is concerned with the implications of Flipped Classroom (FC) model at higher education institutions. There is a wide range of the opinions and experiences on FC model and the model is still being ...
Öğretmenlerin bakışıyla öğretmenlerde tükenmişlik düzeylerinin incelenmesi
(Gazi Üniversitesi Gazi Eğitim Fakültesi Dergisi, 2017-12-05)
Bu çalışmada öğretmenlerde tükenmişlik düzeyleri ile ilgili genel durumun öğretmenlerin bakışıyla
ortaya konması ve tükenmişlik düzeyi ile çeşitli demografik değişkenler arasındaki ilişkinin
incelenmesi amaçlanmaktadır. ...
Synthesis and investigation of antibacterial activities and carbonic anhydrase and acetyl cholinesterase inhibition profiles of novel 4,5-dihydropyrazol and pyrazolyl-thiazole derivatives containing methanoisoindol-1,3-dion unit
(Taylor & Francis, 2017)
Novel 4,5-dihydropyrazole derivatives (3a-i), 3-(4-((3aR,4S,7R,7aS)-1,3-dioxo-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindol-2(3H)-yl)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothio amide, were obtained by the addition ...
Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base
(Wiley, 2017-09)
Compounds containing nitrogen and sulfur atoms can be widely used in various fields, including industry, medicine, biotechnology, and chemical technology. Among them, amides of acids and heterocyclic compounds have an ...
Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines
(Informa, 2017)
4-(3-(4-Substituted-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamides (9-16) were successfully synthesized and their chemical structures were confirmed by H-1 NMR, C-13 NMR, and HRMS spectra. Carbonic ...
Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(-aminoalkyl)phosphinic acid derivatives against human breast cancer
(Wiley, 2017-11)
The aim of this study was to evaluate biologically active novel molecules having potentials to be drugs by their antitumor properties and by activities of apoptotic caspase and topoisomerase. Following syntheses of novel ...
Synthesis of new cyclic thioureas and evaluation of their metal-chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles
(Wiley, 2017-07)
In the presence of trifluoracetic acid (TFAA), an efficient method for the synthesis of tetra(hexa)hydropyrimidinethione-carboxylates has been used on the basis of three-component condensation of thiourea with its different ...
Synthesis of mannich bases by two different methods and evaluation of their acetylcholine esterase and carbonic anhydrase inhibitory activities
(Letters in Drug Design & Discovery, 2017)
Background: Mannich bases are an important compounds in medicinal chemistry. They have wide range of biological activities including carbonic anhydrase (CA) inhibitory and acetylcholine esterase inhibitory (AChE) activities. ...
Weierstrass representation degree and classes of the surfaces in the four dimensional Euclidean space
(Celal Bayar University, 2017)
We study two parameters families of Bour-type and Enneper-type minimal surfaces using the Weierstrass representation in the four dimensional Euclidean space. We obtain implicit algebraic equations, degree and classes of ...