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The synthesis of some beta-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles
(Informa, 2016-12)
beta-Lactam antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a beta-lactam ring in their molecular structures. Synthesis of beta-lactam analogs, which are containing dichloride ...
The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives
(Informa, 2016-01)
Carbonic anhydrases (CAs, EC 4.2.1.1) had six genetically distinct families described to date in various organisms. There are 16 known CA isoforms in humans. Human CA isoenzymes I and II (hCA I and hCA II) are ubiquitous ...
Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions
(Informa, 2016-12)
A series of diaryl ethers were synthesized and their human (h) carbonic anhydrase (CA) isoenzymes hCA I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) inhibitory actions were investigated. The new ...
Investigation of collagenase and elastase inhibitory potential of the novel coordination compound
(Bilgin Kültür Sanat Yayınları, 2021-05-30)
Extracellular matrix (ECM) consist of laminin, collagen, elastin, fibroblasts, and
glycosaminoglycans. Its main role maintain the integrity and strength of organs as well as acts as a
primary barrier to prevent the spread ...
Synthesis, characterization, molecular docking, and biological activities of novel pyrazoline derivatives
(Wiley, 2019)
In this study, synthesis of ethyl 2‐((4‐bromophenyl)diazenyl)‐3‐oxo‐phenylpropanoate
1 was carried out and a series of new 3H‐pyrazol‐3‐ones (P1–7) were synthesized
from 1 as well as various hydrazines. The obtained ...
Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer's disease
(Wiley, 2019-03)
Multiple studies have been recorded on the synthesis and design of multi‐aim anti‐Alzheimer molecules. Using dual butyrylcholinesterase/acetylcholinesterase inhibitor molecules has attracted more interest in the therapy ...
Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials
(Elsevier, 2019-04-16)
Five oxypropanol amine derivatives that four of them are novel have been synthesized with high yields and
practical methods. in vitro antibacterial susceptibility of Acinetobacter baumannii, Pseudomonas aeruginosa,
Escherichia ...
Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer’s disease
(Wiley, 2019-03-25)
Multiple studies have been recorded on the synthesis and design of multi‐aim
anti‐Alzheimer molecules. Using dual butyrylcholinesterase/acetylcholinesterase
inhibitor molecules has attracted more interest in the therapy ...