| dc.contributor.author | Parham, Taslimi | |
| dc.contributor.author | Ilhami, Gulcin | |
| dc.date.accessioned | 2019-05-17T08:18:57Z | |
| dc.date.available | 2019-05-17T08:18:57Z | |
| dc.date.issued | 2017-10 | |
| dc.identifier.uri | http://hdl.handle.net/11772/1197 | |
| dc.description.abstract | -Glycosidase is a catalytic enzyme and it destroys the complex carbohydrates into simple absorbable sugar units. The natural phenolic compounds were tested for their antidiabetic properties as -glycosidase and -amylase inhibitors. The phenolic compounds investigated in this study have been used as antidiabetic common medicines. This paper aimed to consider their capability to inhibit -amylase and -glycosidase, two significant enzymes defined in serum glucose adjustment. These examination recorded impressive inhibition profiles with IC50 values in the range of 137.36-737.23nM against -amylase and 29.01-157.96nM against -glycosidase. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Wiley | en_US |
| dc.relation.isversionof | 10.1002/jbt.21956 | en_US |
| dc.rights | info:eu-repo/semantics/restrictedAccess | en_US |
| dc.subject | Amylase | en_US |
| dc.subject | Glycosidase | en_US |
| dc.subject | Enzyme inhibition | en_US |
| dc.subject | Phenolic compounds | en_US |
| dc.title | Antidiabetic potential: in vitro inhibition effects of some natural phenolic compounds on -glycosidase and -amylase enzymes | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Journal of Biochemical and Molecular Toxicology | en_US |
| dc.contributor.department | Bartın Üniversitesi, Fen Fakültesi, Biyoteknoloji Bölümü | en_US |
| dc.identifier.volume | 31 | en_US |
| dc.identifier.issue | 10 | en_US |
| dc.identifier.startpage | e21956 | en_US |
