Başlık için Biyoteknoloji Bölümü listeleme
Toplam kayıt 116, listelenen: 1-20
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2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, alpha-glycosidase, butyrylcholinesterase, and acetylcholinesterase inhibitory properties
(Elsevier, 2018-03-05)This study contains novel a serie synthesis of N-heterocyclic carbene (NHC) precursors that 2-hydroxyethyl substituted. The NHC precursors have been prepared from 1-(2-hydroxyethyl)benzimidazole and alkyl halides. The novel ... -
Aminopyrazole‐substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties
(Wiley, 2019-02)The synthesis, characterization, aggregation behavior, theoretical studies, and investigation of antimicrobial, antidiabetic, and anticholinergic properties of 4-(2-(5-amino-4-(4-bromophenyl)-3-methyl-1H-pyrazol-1-yl)eth ... -
Anticancer activities and mechanism of action of 2 novel metal complexes, C16H34N8O5Ag2Cd and C11H16N7O2Ag3Ni
(TÜBİTAK, 2014-11-24)The discovery of anticancer activity in cisplatin triggered the development of novel drugs containing metals such as platinum or ruthenium. Extremely diverse structural chemistry and the interaction of metal complexes with ... -
Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes
(Elsevier, 2018-11)The glutathione S-transferase (GST) was purified from fresh blood erythrocytes using affinity column chromatography. Also, alpha-amylase from porcine pancreas and alpha-glycosidase from Saccharomyces cerevisiae were used ... -
Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes
(Wiley, 2018-12)Aldose reductase converts glucose to sorbitol in the polyol pathway. It is an important enzyme to prevent diabetic complications. In this study, we studied the inhibitory effects of bromophenol derivatives on aldose reductase ... -
Antidiabetic potential: in vitro inhibition effects of some natural phenolic compounds on -glycosidase and -amylase enzymes
(Wiley, 2017-10)-Glycosidase is a catalytic enzyme and it destroys the complex carbohydrates into simple absorbable sugar units. The natural phenolic compounds were tested for their antidiabetic properties as -glycosidase and -amylase ... -
Antioxidant activity of the aqueous extract of iris taochia and identification of its chemical constituents
(Indian Journal of Pharmaceutical Sciences, 2018-09)In this study, phytochemical components and antioxidant capacity of extracts obtained from Iris taochia plant, which is endemic to Caucasus, were investigated. Fifteen new compounds were detected and identified using a ... -
Antioxidant activity, acetylcholinesterase, and carbonic anhydrase inhibitory properties of novel ureas derived from phenethylamines
(Wiley, 2016-12)A series of ureas derived from phenethylamines were synthesized and evaluated for human carbonic anhydrase (hCA) I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzyme inhibitory activities and ... -
Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives
(Elsevier, 2015-06)In this study, series of novel bromophenol derivatives were synthesized and investigated for their antioxidant and AChE inhibition properties. Novel brominated diarylmethanones were obtained from the acylation reactions ... -
Antioxidant and anticholinergic properties of olivetol
(Wiley, 2018-06)Olivetol is a pioneer in diverse syntheses of tetrahydrocannabinol. It is produced by a type of insects, which is used as a pheromone, antiseptic, or repellent agent. In this study, we evaluated the antioxidant properties ... -
Cam atıklardan cam yünü eldesi
(KTÜ Proje Pazarı, 2018)Camın temel maddesi en çok beyaz kumda bulunan silis (SİO2) dir. Cam yünü silis kumunun 1200-1250 derecede eritilerek elyaf haline getirilmesi sonucu elde edilmektedir.cam yünü 0,040 /Mk ısı iletim katsayısı ile ısı yalıtımı, ... -
Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep
(Wiley, 2018-08)In this work, the carbonic anhydrase (CA) enzyme was purified from Kangal Akkaraman sheep in Sivas, Turkey with specific activity value of 6681.57 EU/mg and yield of 14.90% with using affinity column chromatography. For ... -
Civa ve gümüşün sıçan karaciğer nad(p)h:kuinon oksidoredüktaz 1 enzimi üzerine in vitro etkileri
(Türk Biyokimya Derneği, 2011-12-02)Kirlenmiş toprak ve sularda bulunan ağır metallerin sağlığa zararlı olduğu bilinmektedir. Bu çalışmada, civa ve gümüşün ksenobiyotik kuinonların detoksifikasyonunda rol alan ve antioksidan olarak da görev yapabilen ... -
Determination of anticancer activities and mechanism of action of a new coordination compound containing Agi(CN)2
(IUPAC (International Union of Pure and Applied Chemistry), 2013-08-12)The main goals of the present study were to determine the anticancer activity of a new cyano-bridged {Ag I (CN) 2} coordination compound, coded as AN5 (C16H34Ag2N8NiO5) on some cancer cell lines in vitro and enlighten it’s ... -
Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia
(Elsevier, 2018-11)Diabetes mellitus (DM) is a chronic metabolic disease in which there are high blood sugar levels over a prolonged period. Aldose reductase (AR) belongs to aldo-keto reductase superfamily and plays a key role in the polyol ... -
Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base
(Wiley, 2017-09)Compounds containing nitrogen and sulfur atoms can be widely used in various fields, including industry, medicine, biotechnology, and chemical technology. Among them, amides of acids and heterocyclic compounds have an ... -
Disiyanogümüş(ı) içeren siyano köprülü koordinasyon polimerinin antimikrobiyal özelliğinin incelenmesi
(GAZİOSMANPAŞA ÜNİVERSİTESİ/FEN EDEBİYAT FAKÜLTESİ/KİMYA BÖLÜMÜ, 2013-06)
