Biyoteknoloji Bölümü Makale Koleksiyonu: Recent submissions
Now showing items 81-91 of 91
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Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases
(Bioorganic Chemistry, 2019-01-24)Mono- or di-substituted imidazole derivatives were synthesized using a one-pot, two-step strategy. All imidazole derivatives were tested for AChE and BChE inhibition and showed nanomolar activity similar to that of the ... -
Novel morpholine liganded Pd-based N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure, antidiabetic and anticholinergic properties
(POLYHEDRON, 2019-02-01)This study involves the synthesis of novel N-heterocyclic carbene (NHC)PdX2(morpholine) complexes (1a-i). These Pd-based complexes are synthesized from pyridine enhanced precatalyst preparation stabilization and initiation ... -
Synthesis, characterization, crystal structure of the coordination polymer Zn(II) with thiosemicarbazone of glyoxalic acid and their inhibitory properties against some metabolic enzymes
(Bioorganic Chemistry, 2019-03)A new coordination polymer Zn(II) with thiosemicarbazone glyoxalic acid H(2)GAT was obtained in this study. According to the X-ray diffraction data, the coordination of the Zn(II) ion is carried out by one sulfur atom, in ... -
Five complexes containing N,N-bis(2hydroxyethyl)-ethylenediamine with tetracyanidopalladate(II): synthesis, crystal structures, thermal, magnetic, and catalytic properties
(Taylor & Francis, 2013-08-14)Five cyanide complexes, [Ni(N-bishydeten)Pd(CN)4]( 1), [Cu(N-bishydeten)Pd(μ-CN)2(CN)2]n (2), [Cu(N-bishydeten)2][Pd(CN)4]( 3), [Zn(N-bishydeten)Pd(CN)4]( 4), and [Cd(N-bishydeten)2][Pd (CN)4]( 5)(N-bishydeten = ... -
In vitro biological properties and predicted DNA–BSA interaction of three new dicyanidoargentate(I)-based complexes: synthesis and characterization
(The Royal Society of Chemistry, 2018-03-01)The reaction of certain metal salts with N,N0-bis(2-hydroxyethyl)ethylenediamine (bishydeten) and [Ag(CN)2] resulted in [Ni(bishydeten)2][Ag(CN)2]2 H2O (C1), [Cu(bishydeten)2Ag2(CN)4] (C2) and [Cd(bishydeten)0.5]2[Ag(CN)2]4 ... -
New bimetallic dicyanidoargentate(I)-based coordination compounds: Synthesis, characterization, biological activities and DNA-BSA binding affinities
(Elsevier, 2017-01-01)Four compounds -two (2 and 3) completely new- of composition [Ni(edbea)Ag3(CN)5] (1), [Cu(edbea)Ag2(CN)4]·H2O (2), [Cd(edbea)Ag3(CN)5]·H2O (3) and [Cd(edbea)2] [Ag(CN)2]2·H2O (4) {edbea; 2,2′-(ethylenedioxy)bis (ethylamine)}, ... -
Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer's disease
(Wiley, 2019-03)Multiple studies have been recorded on the synthesis and design of multi‐aim anti‐Alzheimer molecules. Using dual butyrylcholinesterase/acetylcholinesterase inhibitor molecules has attracted more interest in the therapy ... -
Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors
(Elsevier, 2019-05)A series of substituted pyrazole compounds (1–8 and 9a, b) were synthesized and their structure was characterized by IR, NMR, and Mass analysis. These obtained novel pyrazole derivatives (1–8 and 9a, b) were emerged as ... -
Synthesis and characterization of two novel dicyanidoargentate(I) complexes containing N-(2-hydroxyethyl)ethylenediamine exhibiting significant biological activity
(Royal Society of Chemistry, 2014-07-05)Two novel cyanido-bridged bimetallic polymeric complexes, [Ni(hydeten)2Ag(CN)2] [Ag(CN) 2] H2O(C1) and [Cd2(hydeten)2Ag4(CN)8] H2O( C2) (hydeten: N-(2-hydroxyethyl)ethylenediamine) were synthesized and characterized by ... -
Anticancer activities and mechanism of action of 2 novel metal complexes, C16H34N8O5Ag2Cd and C11H16N7O2Ag3Ni
(TÜBİTAK, 2014-11-24)The discovery of anticancer activity in cisplatin triggered the development of novel drugs containing metals such as platinum or ruthenium. Extremely diverse structural chemistry and the interaction of metal complexes with ... -
Two new coordination polymers containing dicyanidoargentate(I) and dicyanidoaurate(I): synthesis and characterization, and a detailed in vitro investigation of their anticancer activities on some cancer cell lines
(TÜBİTAK, 2015-02-16)Two novel cyanido-bridged bimetallic polymeric complexes, [Ni(edbea)Ag3 (CN)5]n (C1) and [Ni(bishydeten) Au2 (CN)4 ]n (C2), where edbea = [2,2′-(ethylenedioxy)bis(ethylamine)] and bishydeten = [(N ,N′-bis(2-hydroxyethyl) ...
