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Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases

Kuzu, Burak; Tan, Meltem; Taslimi, Parham; Gülçin, İlhami; Taşpınar, Mehmet; Menges, Nurettin (Bioorganic Chemistry, 2019-01-24)

Mono- or di-substituted imidazole derivatives were synthesized using a one-pot, two-step strategy. All imidazole derivatives were tested for AChE and BChE inhibition and showed nanomolar activity similar to that of the ...