Konu "Modeling" için Biyoteknoloji Bölümü Makale Koleksiyonu listeleme

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Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes

Cem, Yamali; Halise Inci, Gul; Abdulilah, Ece; Taslimi, Parham; Ilhami, Gulcin (Wiley, 2018-04)

In this study, 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides were synthesized, and inhibition effects on AChE, hCA I, and hCA II were evaluated. K-i values of the compounds toward hCA I were ...