Browsing Biyoteknoloji Bölümü Makale Koleksiyonu by Subject "Topoisomerase"

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Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(-aminoalkyl)phosphinic acid derivatives against human breast cancer

Ilhami, Gulcin; Taslimi, Parham; Dastan, Taner; Koçyiğit, Ümit M.; Dastan, Sevgi Durna; Kılıçkaya, Pakize Cantürk; Çevik, Özge; Koparır, Metin; Orek, Cahit; Çetin, Ahmet (Wiley, 2017-11)

The aim of this study was to evaluate biologically active novel molecules having potentials to be drugs by their antitumor properties and by activities of apoptotic caspase and topoisomerase. Following syntheses of novel ...